Figure 7 shows a relatively sparse representation of pathway networks for IGHV-mutated CLL patients in comparison to Figure 6. Two major networks are visible which mainly include IL8, CXCR1, mTOR-pathway and CDC42 signals. The enrichment called biocarta ppara in Figure 6 and Figure 7 refers to the Mechanism of Gene Regulation by Peroxisome Proliferators via PPAR alpha. This evidence concerns the gene CXCR1 and B-cell chronic lymphocytic leukemia.