GPLD1 and type 1 diabetes mellitus: Importantly, there was no correlation between the plasma HDL-cholesterol or HDL-apo A-I concentrations and the interaction of serum GPLD1 with micelle-like bAChE complexes (Figure 4) or serum GPLD1 activity/protein [30] (Figure 1): Taken together, the inverse regulation of the HDL parameters in type 1 (up compared to control) and type 2 (down compared to control) diabetic patients was faced by uniform upregulation of the serum GPLD1 parameters in diabetes type 1 and 2.