DDX11 and osteosarcoma: In conclusion, this study has revealed that DDX11-AS1 regulates DDX11 gene expression in osteosarcoma cells with a dual mechanism: on one hand it sequesters miR-873-5p preventing it from silencing the DDX11 mRNA through RISC; on the other hand, it associates with the IGF2BP2 protein factor supporting its stabilizing effect on DDX11 mRNA [59].