For instance, screening of 31 cancer types, including tumours and non-neoplastic tissue samples, revealed that 95% of them displayed telomerase activity and of that 53% displayed altered TERT promoter methylation, 31% TERT promoter mutations, 3% TERT amplification, 3% TERT structural variants, and 5% TERT promoter structural variants. This evidence concerns the gene TERT and neoplasm.