Increased COX-2 expression was not only found in a variety of gynecological tumors such as endometrial carcinoma [57], breast carcinoma [58,59,60], ovarian carcinoma [61], or cervical carcinoma [62], but also in a lot of other tumor entities [63,64,65,66,67,68]. This evidence concerns the gene PTGS2 and female reproductive system neoplasm.