MKI67 and colorectal cancer: Darwito et al. found decreased Ki67 expression in breast cancer patients receiving 1 g per day of n-3 supplement (39.2 ± 5.3 versus 42.4 ± 4.8, p = 0.03) [8], while there were no observed changes in the Ki67 proliferation index in patients with colorectal cancer and liver metastases when supplemented with 2 g of EPA per day [36].