These contain both neoantigens (such as different junction peptides derived from BCR-ABL1 fusion protein), as well as antigens derived from overexpressed proteins, such as Wilms’ tumor protein (WT1), preferentially expressed antigen in melanoma (PRAME), proteinase 3 (PR3) or neutrophil elastase (ELA2) [44]. The gene discussed is WT1; the disease is melanoma.