Therefore, in addition to CD34, which is not uniquely expressed on AML LSCs, the presence of CD25, CD32, CD38, CD44, CD47, CD96, CD123, CLL-1 (C-type lectin-like molecules-1), TIM3 (T-cell immunoglobulin and mucin-domain containing-3) were proposed as specific for AML LSCs [22,23,24,25]. This evidence concerns the gene CD44 and acute myeloid leukemia.