STAT3 and cancer: Previously, we reported that (E)-N-(5-benzylthiazol-2-yl)-3-(furan-2-yl) acrylamide (aminothiazole, ATZ-502) showed cytotoxic effects in several cancer cells by blocking the function of KPNB1 with pSTAT3, STAT3, EGFR, and ErbB2 [18,19,20,21].