In the human cisplatin-resistant ovarian cancer cell lines A2780/CP70 and MCAS, β-elemene was found to increase the susceptibility to cisplatin through the regulation of DNA repair activity including the expression inhibition of excision repair cross-complementation group-1 (ERCC-1) and the induction of apoptosis, including the increased phosphorylate level of JNK and the downregulation of XIAP expression [66,67]. The gene discussed is ERCC1; the disease is ovarian cancer.