When the study population was divided into the responder and non-responder groups, AUC for the non-responder group with the duration between the onset of symptoms and admission, pleural effusion, MP-specific IgM titer at the time of admission, oxygen need, rhinovirus co-infection, and LDH levels, which were identified to be significantly associated factors, was 0.8076 (Figure 1E). The gene discussed is CD40LG; the disease is coinfection.