Similarly, Mitogen-Activated Protein Kinase 4 (MAPK4) in 12 cancers, Serine/Threonine Kinase 32A (STK32A) and P21 (RAC1) Activated Kinase 3 (PAK3) in 10 cancers were found to be commonly downregulated. This evidence concerns the gene MAP3K4 and cancer.