Among the 148 dark kinases included in our analysis, PKMYT1 (in 17 cancers), Mitogen-Activated Protein Kinase 15 (MAPK15) in nine cancers, CaM Kinase Like Vesicle Associated (CAMKV) in 8 cancers), PNCK and STK31 (in seven cancers) were commonly upregulated. The gene discussed is MAPK15; the disease is cancer.