Growth factor cocktails vary according to the source tumour, but often contain combinations of Wnt, R-Spondin-1 (a Wnt amplifier), epidermal growth factor (EGF), prostaglandin E2, fibroblast growth factor 10 (FGF10), noggin (inhibitor of bone morphogenetic protein signalling), A83-01 (inhibitor of TGF-signalling), SB202190 (p38 inhibitor) and Y-27632 (Rho/ROCK kinase inhibitor) [21]. This evidence concerns the gene EGF and neoplasm.