Four unrelated BmDV or BmBDV infection’s resistance genes, such as nonsusceptibility gene against BmDNV-1 (nsd-1) [18], Non-infectious gene against BmDNV-1 (Nid-1) [19], nonsusceptibility gene against BmDNV-2 (nsd-2) [20], and nonsusceptibility gene against Zhenjiang (China) strain of BmDNV (nsd-Z) [21] were reported thus far (Table 1). Here, NSD2 is linked to infection.