PRDM15 and chronic obstructive pulmonary disease: One report evaluated the ancestral genetic contribution and SNPs associated with the risk of COPD in a Latin American population characterized by a higher proportion of European ancestry (55.93% ± 6.89) and Mapuche ancestry (35.11% ± 8.54); in this study, the authors reported alleles in PRDM15 associated with protection against COPD and SNPs in PPP1R12B associated with susceptibility [21].