In particular, intestinal-type gastric cancer (GC) cells express extremely low levels of ELOVL5 and FADS1 due to hypermethylation at the promoter region and are resistant to ferroptosis, while mesenchymal-type GC cells are sensitive to ferroptosis at high levels of ELOVL5 and FADS1 [63]. The gene discussed is ELOVL5; the disease is gastric cancer.