Accordingly, K+ recycling genes were shown to be indispensable for the process of hearing, as evidenced by the fact that multiple mutations in these genes (GJB1 (Cx32), GJB2 (Cx26), GJB3 (Cx31), GJB4 (Cx30.3), GJB6 (Cx30), KCNE1, KCNQ1, and KCNQ4) lead to both syndromic and nonsyndromic forms of hearing loss [6,14,15]. The gene discussed is KCNQ4; the disease is hearing loss disorder.