Two SNPs, the rs2070358 G allele in KCNE1 and rs34287852 G allele (c.1365T>G, p.H455Q) in KCNQ4, were reported to be significant in both populations, with the rs2070358 G allele increasing the susceptibility to noise-induced hearing loss [7,49]. The gene discussed is KCNE1; the disease is hearing loss disorder.