Figure 4B shows an example of a CTC expressing epithelial markers CK8/18, EpCAM and E-cadherin in addition to EMT markers Vimentin, Twist-1, as well as several prostate cancer markers, including AR-V7. It also expressed phospo-p38, which has been previously linked to survival and resistance and which was associated with Twist-1 by clustering (Figure 2C). The gene discussed is KRT8; the disease is Familial prostate cancer.