None of the SK-N-BE(2) tumor-engrafted mice intravenously treated with 1 × 106 L1CAM-SS-4-1BB/ζ or L1CAM-LS-4-1BB/ζ CD8+ murine T cells showed increased bioluminescence at the tumor site (Figure 2A,B). The gene discussed is L1CAM; the disease is neoplasm.