Individuals with high total tissue PDCD4 expression had longer survival from the time of brain metastasis diagnosis (log-rank test, p = 0.026; RR 0.54; Lower CL 0.3; Upper CL 0.93) (Figure 4f), and the same was seen in cases with high nuclear PDCD4 tumor cell expression (log-rank test, p = 0.004). This evidence concerns the gene PDCD4 and neoplasm.