HCC cells treated with CDCA8-1siRNA migrated more slowly than cells treated with a control siRNA (Figure 3C), causing strong inhibition of cell migration of about 50% and 70% in Huh1 and Huh7 cells, respectively, after 96 h of target siRNA treatment (Figure 3D). The gene discussed is CDCA8; the disease is hepatocellular carcinoma.