The protective role of miR206 in ALS could also be due to its role in satellite cell differentiation: miR206 promotes the differentiation of satellite cells into muscle cells by inhibiting PAX7 expression; PAX7 inhibition is further enhanced by a positive feedback loop in which the muscular differentiation factors MyoD, myogenin, and MEF2 induce miR206 transcription [78,79,80]. Here, MYOD1 is linked to amyotrophic lateral sclerosis.