In an application to the TCGA GBM dataset, WSNF was built on gene expression data and information from a complex miRNA-TF-mRNA regulatory network, with the nodes representing the features, i.e., miRNA, transcription factors (TF), and mRNAs, and the edges of the interactions between them, the latter retrieved from interatomic databases. The gene discussed is TF; the disease is glioblastoma.