Analysis using the The Cancer Genome Atlas (TCGA) dataset and datasets available in the Gene Expression Omnibus (GEO) database revealed the inverse correlation of the IGFBP3 (encoding the IGFBP-3 protein) mRNA expression with a mesenchymal marker VIM (encoding the vimentin protein) and the positive correlation between IGFBP3 mRNA and CDH1 mRNA (encoding the E-cadherin protein) in tumors of patients with NSCLC (Figure S1), confirming the regulation of the EMT program by IGFBP-3. The gene discussed is VIM; the disease is non-small cell lung carcinoma.