Additionally, DHA and EPA decreased interleukin (IL)-6-induced C-reactive protein in HepG2 liver cancer cells by inhibiting STAT3 activity [12], which plays an important role in KRAS-induced pancreatic cancer growth and progression [13], suggesting that n-3 PUFAs can regulate intracellular inflammatory cytokines to influence KRAS-driven cell survival and the growth of pancreatic cancer. This evidence concerns the gene KRAS and pancreatic neoplasm.