FGL1 and familial pancreatic carcinoma: Notably, significantly higher levels of EPA, EPA-mediated hydroxyeicosapentaenoic acid (HEPE), resolvin E1, and resolvin E2 production were recorded in SUIT-2 cells with HPS knockdown (Figure 4A,B), implying that HPS expression is involved in regulating n-3 and n-6 PUFA metabolism and pancreatic cancer cell growth.