ERBB2 and cancer: Since the ERBB2-expressing cancer cell lines, BT474, SKBR3, MDA-MB-361, MCF7, and OE19, used by the other studies [17,18,28] also express EGFR [48,49,50], the lapatinib-induced autophagy promotion reported by these studies may be due to lapatinib inhibition of EGFR.