The specific aims were to evaluate the distribution of variants of IL-1B genes (at loci -31 and -511) and IL-1RA in patients after ACS, compare them with results of other studies, and try to determine the characteristics of patients (at their first ACS) in terms of the most frequent IL-1B and IL-1RN genetic variants, including the age at which they had their first ACS and the degree of coronary atherosclerosis assessed during coronary angiography performed during that episode. This evidence concerns the gene IL1B and coronary atherosclerosis.