Three genes (POLR2A, ZNF592, TRAPPC12) differentiating LEAD from AAA and 12 genes (RP11-262D11.2, SRRM1P3, SDCBPP2, ARL6IP1, HNRNPA1P7, API5P1, AC104651.2, EIF3FP3, RP11-286H14.4, CTNNA1P1, DYNC1I2P1, CTB-52I2.4) differentiating LEAD and CVD were also correlated with creatinine levels (Table 3). This evidence concerns the gene API5P1 and triple-A syndrome.