Additionally, a curative study carried out with L. fermentum CECT5716 in the same TNBS model in rats showed its effect in the late phase of colitis, being able to decrease leukotriene B4 (LTB4) production, Il-6 expression, and Toll-like receptor (TLR)/MyD88 function [95]. The gene discussed is IL6; the disease is colitis.