To restrict ourselves to the genes included in Figure 3, it can be mentioned that SLC2A4RG, which is repressed by ZNF518B, has recently been validated as tumour suppressor of human glioma [40], while PTBP2, also inhibited by ZNF518B, favours metastasis in CRC by activating the transcription of RUNX2 [41]. The gene discussed is RUNX2; the disease is central nervous system cancer.