Of these, 44 had mutations in 11 genes responsible for high myopia eye disease, including COL2A1, COL11A1, PRPH2, FBN1, GNAT1, OPA1, PAX2, GUCY2D, TSPAN12, CACNA1F and RPGR. The initial clinical records of the 71 patients with mutations did not show any diseases other than high myopia. The gene discussed is COL2A1; the disease is eye disorder.