IL6 and ovarian carcinoma: Furthermore, the immunosuppressive cytokines produced by PRAT, such as IL-10, along with the suppression of IL-6, IL-12p40, and CD86 result in stimulation of ovarian cancer progression, while stimulation of IFNγ, by abrogating IL-12 inhibition, leads to a favorable prognosis in malignant ascites [77].