In addition, rs1213265 in PTGS1 showed significant associations with benign breast tumors (OR = 1.81, 95% CI: 1.29–2.53, p = 6.03 × 10−4) and osteoporosis (OR = 2.03, 95% CI: 1.36–3.03, p = 4.90 × 10−4). The gene discussed is PTGS1; the disease is osteoporosis.