PTGS1 and osteoporosis: In the case of the PTGS1 gene, the rs1213265 and rs3119773 variants significantly increased the risk of benign breast tumors (OR = 1.89, 95% CI: 1.23–2.88, p = 3.38 × 10−3; OR = 1.88, 95% CI: 1.23–2.88, p = 3.41 × 10−3, respectively) and osteoporosis (OR = 2.88, 95% CI: 1.36–3.85, p = 1.93 × 10−3; OR = 2.28, 95% CI: 1.35–3.84, p = 1.99 × 10−3, respectively) (Table 3).