In another study, PIWIL3/OIP5-AS1/miR-367-3p/CEBPA (CCAAT/enhancer binding protein alpha) feedback loop was found to regulate glioma cell growth, and the overexpression of PIWIL3 or piR-30188, either jointly or separately suppressed glioma progression [218]. The gene discussed is CEBPA; the disease is central nervous system cancer.