For example, although histone demethylase inhibitors are thought to be ineffective against JARID2 due to its lack of true demethylase activity, additional investigations into the role of JARID2 in endometriosis could uncover alternate options to therapeutically regulate it, such as dihydroartemisinin which has been used in prostate cancer [73]. The gene discussed is MBD2; the disease is prostate carcinoma.