SOD1 and familial hyperaldosteronism: The SOD activity in the colon tissue of the DB (0.11 ± 0.03 U/mg protein) and FH groups (0.08 ± 0.02 U/mg protein) significantly (p < 0.05) increased compared to the DSS group (0.05 ± 0.01 U/mg protein) (Figure 4B).