TGFB1 and cancer: In physiological conditions these cells have a key role in preventing autoimmunity, but in cancer they promote tumor growth by releasing protumor and anti-inflammatory cytokines, such as interleukin 10 (IL-10) or transforming growth factor β (TGF-β), and proangiogenic molecules, such as vascular endothelial growth factor (VEGF) [5,6,10,11].