Next, to determine the genetic causes of OCA segregating in these nine families, Sanger sequencing of coding and non-coding exons of all six known OCA genes (TYR (OCA1), OCA2(OCA2), TYRP1 (OCA3), SLC45A2 (OCA4), SLC24A5 (OCA6) and C10ORF11 (OCA7)) was performed for the proband of each family. The gene discussed is SLC45A2; the disease is oculocutaneous albinism.