Next, to determine the genetic causes of OCA segregating in these nine families, Sanger sequencing of coding and non-coding exons of all six known OCA genes (TYR (OCA1), OCA2(OCA2), TYRP1 (OCA3), SLC45A2 (OCA4), SLC24A5 (OCA6) and C10ORF11 (OCA7)) was performed for the proband of each family. This evidence concerns the gene LRMDA and oculocutaneous albinism.