Figure 2 shows a comparison of the ROC curves of these three immunological markers for the prediction of histological chorioamnionitis. TNF-α and MMP-8 predicted chorioamnionitis with AUCs of 0.91 and 0.89, respectively, while IL-6 predicted chorioamnionitis with an AUC of 0.81. The DeLong test demonstrated that TNF-α and MMP-8 have significantly different AUCs from IL-6, with a p-value < 0.05. No statistically significant difference was found for the comparison between the ROC curves of TNF-α and MMP-8 (p-value = 0.5). Here, TNF is linked to chorioamnionitis.