IL1B and viral infectious disease: Ingenuity pathway analysis (Figure 4a) confirmed regulation of the immune system by highlighting how miR31-5p and miR615-5p control CXCL8, C-X-C Motif Chemokine Ligand 8 activated in viral infections and miR584-5p/miR148-5p control TMEM9, which enhances production of proinflammatory cytokines induced by TNF, IL1B, and TLR ligands [31].