CD8A and neoplasm: Intensive and invasive growth of the tumor can lead to minor disruptions of the surrounding tissue by induction of inflammatory processes, which can be monitored by the recruitment of immune cells, such as NK cells, dendritic cells (DCs), or macrophages followed by the infiltration of tumor-specific CD4+ and CD8+ T cells to the tumor site in order to attack the remaining antigen-bearing tumor cells [8].