CASP8 and lung cancer: Among the genotypes possibly associated with lung cancer risk were Val318Leu of the CASP-5 gene (OR = 2.47, 95% CI: 1.07–5.69, p = 0.03), Lys441Arg of the DR4 gene (OR = 1.89, 95% CI: 1.05–3.40, p = 0.03), and His302Asp for CASP-8 (OR = 2.26, 95% CI: 1.18–4.31, p = 0.02) [26].