NPPB and hydrops fetalis: The results of the multivariate analysis revealed that after the adjustment for age, BMI, NYHA functional class III, LVEF, serum albumin, eGFR, and log BNP, inadequate calorie intake defined as <60% of the estimated calorie requirement was a significantly independent predictor of adverse clinical events including all-cause death and HF-related hospitalization over 1 year in the patients with chronic HF (Table 3).