In this setting, if there are two different NSCLC patients with ambulatory status and serum albumin falling into the same category, decisions for two patients would be the same according to the NESMS, even if the two have significantly different biological profiles (e.g., synchronous metastasis with a positive EGFR mutation versus metachronous metastasis without EGFR mutation). The gene discussed is ALB; the disease is non-small cell lung carcinoma.