PGP and Carcinoma, Lewis Lung: Following two hours of incubation with CUR, the solid dispersion formulation, and its physical mixture led to the differential cytotoxic activity of paclitaxel via the suppression of the P-gp-induced efflux of paclitaxel in P-gp overexpressing MDA-MB-231 and Lewis lung carcinoma-PK1-P-gp cells.