This highlights the potential role of these miRNAs to act as indirect regulators of myogenic gene expression through their regulation of Camk2a. CAMK2 has been implicated in disorders of both cardiac and skeletal muscle such as cardiac ischemia [54], arrhythmias [55], and limb girdle muscular dystrophy [56]. The gene discussed is CAMK2A; the disease is myocardial ischemia.