VCAM1 and triple-A syndrome: Wang et al. used ultrasound microbubbles coupled with a VCAM-1-targeted single-chain antibody (scFvmVCAM-1) and a miRNA-126mimic (M126) as carriers, enabling a theranostic approach (TargMB-M126) with simultaneous molecular imaging and targeted therapy of AAA in a mouse model of AAA [81] (please also refer to Figure 4).