Further, even though lncRNA-SNHG14 acts as a gemcitabine resistance factor in PaC (Section 4.2.9), lncRNA-SNHG14 is able to suppress invasion and promote apoptotic cell death via sponging miR-92a-3p in glioblastoma [231], showing its dual role in cancer (also see Section 4.2.1 about the dual role of circ-HIPK3). This evidence concerns the gene HIPK3 and cancer.