SAMD14 and benign prostatic hyperplasia: To assess whether SAMD14 overexpression in HMC-1 cells could alter prostate epithelial tumor phenotype, fluorescently-labelled BPH-1 prostate epithelial cells co-cultured with NPF or CAF or CAF supplemented with HMC-1 or HMC-1-SAMD14+ conditioned media over a period of 24 h (Figure 5a).