The normalized mRNA expression of general CAF markers, including FAP, ACTA2, MFAP5, COL11A1, VIM, PDGFRA, PDGFRB, and POSTN, were compared between 44 normal samples and 522 HNSCC tissues to identify the CAF markers upregulated in HNSCC. Here, POSTN is linked to head and neck squamous cell carcinoma.