Mutations in ASXL1 are frequently found in a variety of myeloid neoplasms, such as MDS, AML, MPNs, and CMML, as well as age-related clonal hematopoiesis in healthy individuals [5,6,8,9,10,94,95,96,97,98]. The gene discussed is ASXL1; the disease is myelodysplastic syndrome.